منابع مشابه
Papilledema secondary to Burkitt lymphoma.
El linfoma de Burkitt (LB) es un tipo de linfoma no odgkin de células B de crecimiento rápido que afecta niños y adultos jóvenes y que puede presentarse de orma endémica en África, esporádicamente o asociada a nmunodeficiencias. De comienzo brusco y crecimiento agreivo, se produce por la traslocación en el gen c-Myc del romosoma 81. Fue descrito en el año 1958 por el ciruano irlandés Denis Pars...
متن کاملSporadic Burkitt Lymphoma: A Case Report
Introduction: Burkitt lymphoma is an aggressive subtype of Hodgkin lymphoma with a doubling time of 25 hours. It is characterized by a MYC gene coding alteration which results from a translocation of chromosome 8 on the MYC gene locus and immunoglobulin heavy-chain locus (IGH) on chromosome 14. Even though HIV infection is associated to an increased risk of Burkitt lymphoma, th...
متن کاملEBNA promoter usage in EBV-negative Burkitt lymphoma cell lines converted with a neomycin-resistant EBV strain.
Latent Epstein-Barr virus (EBV) uses two alternative strategies to express the Epstein-Barr nuclear antigens (EBNAs). Resting normal B cells harboring latent virus and Burkitt's lymphoma (BL) cells use monocistronic messages generated from the Q promoter (restricted strategy). EBV-transformed immunoblasts express all EBNAs by using giant messages generated from the W/C promoter (full program). ...
متن کاملUnveiling Another Missing Piece in EBV-Driven Lymphomagenesis: EBV-Encoded MicroRNAs Expression in EBER-Negative Burkitt Lymphoma Cases
Epstein-Barr virus (EBV) is a gammaherpesvirus linked to a number of lymphoid and epithelial malignancies, including Burkitt lymphoma (BL) in which its frequency ranges from 30% in sporadic cases to 100% in the endemic ones. The possible contribution of EBV to BL pathogenesis is largely unknown. It has been suggested that EBV may be associated with all of the cases, including those diagnosed as...
متن کاملDiagnosis of Burkitt Lymphoma
Clinical presentation in extranodal and nodal sites of rapidly expanding masses in high-risk populations suggests Burkitt lymphoma (BL). Most patients present with advanced disease because of the rapid rate of tumor growth. BL cells have a remarkably short doubling time. Children in equatorial Africa and Papua New Guinea have endemic BL and present with facial tumors in the jaw or orbit, abdomi...
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ژورنال
عنوان ژورنال: Blood
سال: 2020
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood.2020005492